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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK13
All Species:
12.73
Human Site:
S1225
Identified Species:
31.11
UniProt:
Q14004
Number Species:
9
Phosphosite Substitution
Charge Score:
0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14004
NP_003709.3
1512
164923
S1225
L
R
P
P
P
E
P
S
T
P
V
S
G
Q
D
Chimpanzee
Pan troglodytes
XP_001139939
1512
164915
S1225
L
R
P
P
P
E
P
S
T
P
V
S
G
Q
D
Rhesus Macaque
Macaca mulatta
XP_001088594
1490
164086
E1229
E
P
A
G
S
L
E
E
N
N
S
D
K
N
S
Dog
Lupus familis
XP_533082
1377
150158
S1091
L
R
P
P
P
E
P
S
T
P
A
S
G
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZA1
1511
164590
S1224
L
R
P
P
L
E
P
S
T
P
G
S
G
Q
D
Rat
Rattus norvegicus
Q3MJK5
1484
163772
E1225
E
P
A
G
N
L
E
E
N
T
S
D
K
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425866
1032
115177
E774
F
P
I
T
A
I
R
E
I
K
I
L
R
Q
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687417
1286
141523
P1028
L
P
E
S
E
R
P
P
E
P
P
A
L
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46551
730
82410
E472
L
A
R
L
W
E
K
E
S
R
L
Y
T
N
R
Sea Urchin
Strong. purpuratus
XP_789337
1264
139419
G1006
G
A
L
E
Q
V
F
G
P
S
S
S
E
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
41.4
82.5
N.A.
95.1
41.6
N.A.
N.A.
29.7
N.A.
44
N.A.
N.A.
N.A.
24.6
32.6
Protein Similarity:
100
99.8
53.5
84.5
N.A.
96.8
53.9
N.A.
N.A.
37.9
N.A.
55
N.A.
N.A.
N.A.
33.3
46.9
P-Site Identity:
100
100
0
93.3
N.A.
86.6
0
N.A.
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
0
93.3
N.A.
86.6
0
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
20
0
10
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
40
% D
% Glu:
20
0
10
10
10
50
20
40
10
0
0
0
10
0
0
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
20
0
0
0
10
0
0
10
0
40
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
10
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
10
0
0
20
0
20
% K
% Leu:
60
0
10
10
10
20
0
0
0
0
10
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
20
10
0
0
0
30
0
% N
% Pro:
0
40
40
40
30
0
50
10
10
50
10
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
60
0
% Q
% Arg:
0
40
10
0
0
10
10
0
0
10
0
0
10
0
10
% R
% Ser:
0
0
0
10
10
0
0
40
10
10
30
50
0
0
20
% S
% Thr:
0
0
0
10
0
0
0
0
40
10
0
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
20
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _